iPRF (injectable Platelet-Rich Fibrin) is a next-generation anti-aging and regenerative treatment that uses your own blood to stimulate natural healing, collagen production, and tissue regeneration. Unlike traditional PRP, iPRF contains a fibrin matrix that releases growth factors more gradually, providing longer-lasting rejuvenation.
iPRF can be used for both skin rejuvenation and hair restoration, making it a versatile solution for aesthetic and regenerative purposes.
Learn more about which treatment is right for you in our Blog
iPRF is suitable for a variety of skin and hair concerns, including:
Skin rejuvenation and biostimulation
Fine lines and wrinkles
Under-eye dark circles and puffiness
Acne scars and post-inflammatory marks
Improvement in skin texture and elasticity
Collagen stimulation for firmer, younger-looking skin
Hair restoration for androgenetic alopecia
Strengthening and stimulating dormant hair follicles
By delivering concentrated growth factors directly to the treatment area, iPRF supports natural regeneration and long-term improvement in skin and hair health.
iPRF treatment may not be suitable if you have certain medical conditions or risk factors. Contraindications include:
Thrombocytopenia or platelet disorders
Active infection at the treatment site
Recent illness or fever
Pregnancy or breastfeeding
Systemic use of corticosteroids within 2 weeks
Corticosteroid injections at the treatment site within 1 month
Chronic liver disease or cancer
Low haemoglobin (<10 g/dL) or low platelet count (<150 x 10⁹/L)
Use of anticoagulants or consistent NSAID use
A detailed medical history is taken during your consultation to ensure the treatment is safe for you.
Initial consultation
Before your iPRF treatment at Credo Aesthetics in Bristol:
Please attend your appointment with a clean face, free from makeup, creams, or lotions.
For scalp treatments, ensure your hair has been freshly shampooed before your visit.
To help optimise your results:
Increase your intake of Vitamins B and C for two weeks before treatment.
Stay well hydrated.
Avoid alcohol and non-steroidal anti-inflammatory drugs (NSAIDs) for at least 48 hours before your appointment.
During the consultation, a qualified practitioner will assess your suitability, discuss your goals, and explain the procedure in detail.
Treatment Procedure
A small blood sample is taken (typically 10–20 mL)
The sample is processed to create iPRF
The treatment area is cleansed thoroughly
An anaesthetic cream is applied and removed
iPRF is injected into the skin or scalp using precise techniques
Treatment time varies by area, usually 45–60 minutes.
After care
To support optimal healing and results, please follow these guidelines:
Avoid touching the treated area(s).
Do not wash the treated area(s) for at least 8 hours.
After 8 hours, gently cleanse with running water and apply a light moisturiser if needed.
Do not apply ice, lotions, foundation, or other makeup products for 24 hours.
Avoid activities that cause excessive sweating for 2–3 days.
Refrain from alcohol consumption and smoking for 2–3 days.
Begin applying a Vitamin C serum and/or taking oral Vitamin C 2–3 days after treatment.
Avoid tanning beds and excessive sun exposure.
Do not exfoliate or undergo chemical peels for 1–3 weeks.
Avoid aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) unless medically necessary.
For best results and proper healing:
Do not shampoo your hair on the day of treatment.
Avoid rubbing or touching the treated area.
Do not apply ice packs to the scalp.
Refrain from vigorous exercise, sun exposure, and heat (e.g., saunas, steam rooms) for 2–3 days.
Avoid alcohol and smoking for 2–3 days.
Do not colour, straighten, or apply hair products for at least 3 days.
Avoid aspirin and other NSAIDs unless prescribed by your healthcare provider
iPRF is often combined with Medical Microneedling to supercharge skin rejuvenation.
Recommended Number and Frequency of Treatments
2–6 sessions, spaced 4 weeks apart, depending on skin condition
Maintenance: 4 sessions every 4–6 weeks
4–6 sessions, spaced 4 weeks apart
Maintenance: 4 sessions, 6 weeks apart
Your practitioner will create a personalised treatment plan based on your goals and response.
Procedure time
30-45 minutes
Risk & complications
Low
Down time
None, however, your skin can look red for a few hours
1–2 weeks: Glow, mild plumpness, hydration boost
4–6 weeks: Fine lines soften, texture improves, pores shrink
6–12 weeks: Collagen remodelling, firmer and brighter skin
3–6 months: Maximum tightening, improved elasticity, wrinkle reduction
Yes. iPRF uses your own blood, making it a natural, biocompatible treatment with a strong safety profile when performed by a qualified practitioner.
Most clients find iPRF comfortable. Sensation varies depending on the area treated, but anaesthetic cream can be applied to improve comfort.
Some improvement may be noticed after the first session. Full results develop gradually over several weeks as collagen production increases.
Most clients benefit from 2–6 sessions for skin rejuvenation or 4–6 sessions for hair restoration. Maintenance treatments may be recommended.
Results vary but can last several months. Regular maintenance sessions help prolong the benefits.
Both use your own blood, but:
PRP: liquid plasma with rapid growth factor release
iPRF: fibrin matrix with slower, sustained release
iPRF provides longer-lasting rejuvenation and may be preferable for clients seeking gradual, durable results.
Treatment prices
Face £200 | Scalp £250
With or without microneedling
Treatment booking deposit: £200